AdvisorShares Pure US Cannabis ETF (MSOS), an exchange-traded fund specialized in the cannabis industry in the United States, has experienced a meteoric rise after President Donald Trump’s social network, Truth Social, highlighted the health benefits of cannabis for older adults.
Launched on September 1, 2020, and managed by AdvisorShares Investments, it is the largest marijuana ETF by market capitalization, with approximately 973 million dollars in assets under management (AUM).
On Sunday, September 28, Truth Social posted that cannabidiol (CBD) derived from hemp could “revolutionize healthcare for older adults” by helping to slow disease progression and was shown to be an alternative to prescription medications.
In addition, President Trump had stated last month that his administration was seeking to reclassify marijuana, which could also result in a possible easing of criminal penalties for its use.
The reclassification would remove the tax burden that denies standard business deductions to cannabis companies. If the tax barrier is resolved, it could pave the way for more cannabis companies to be listed on U.S. stock exchanges and attract interest from institutional investors.
Booming Sector Companies and ETFs
Exchange-traded funds from AdvisorShares (MSOS) and Roundhill are on track for their largest recorded quarterly gains, each exceeding 70%, according to Reuters.
The AdvisorShares Pure US Cannabis ETF (MSOS) actively invests at least 80% of net assets in U.S. companies that derive a minimum of 50% of their revenue from the cannabis or hemp business. It may also use financial derivatives related to this same sector.
The ETF’s portfolio is diversified across approximately 96 securities, although concentration is high: the top 10 positions represent more than 98% of the assets. This reflects a clear focus on leading companies in the segment.
As of 2025 data, the AdvisorShares Pure US Cannabis ETF (MSOS) is the largest ETF in the cannabis segment by assets under management, followed distantly by other index funds such as the Amplify Alternative Harvest ETF and the AdvisorShares Pure Cannabis ETF (YOLO).
